PRIME (Positive Transitions Through the Menopause)

Chief Investigator: Shema Tariq
The number of women accessing HIV care aged 45-60 (potentially menopausal age) has increased from around 400 in 2000, to over 8500 in 2014 (approximately a third of all women accessing HIV care). The PRIME study (Positive tRansItions through the MEnopause) is an NIHR-funded mixed-methods observational study that will explore the impact of the menopause on HIV-positive women’s wellbeing (e.g. sexual functioning, quality of life and mental health) and engagement with HIV care (e.g. adherence to antiretroviral therapy and HIV clinic attendance). We are recruiting 1500 HIV-positive women aged 45-60 from clinics across England. We are admistering self-completed paper questionnaires to participants, collecting data from clinical databases and conducting semi-structured interviews with a proportion of women. We are also seeking consent for ongoing follow-up in the longer term. In establishing a cohort of women ageing with HIV, we are developing a unique resource for further research and collaborative work.
Please contact Shema Tariq on s.tariq@ucl.ac.uk if you would like to know more about the study or follow us on Twitter.

POPPY

Chief Investigators: Alan Winston and Caroline Sabin
Several reports have suggested age-associated co-morbidities occur earlier in HIV-positive subjects on effective antiretroviral therapy compared to HIV-negative subjects. However, the control populations within these studies are not always closely matched to the HIV-positive populations and therefore such findings require to be interpreted with caution. POPPY has recruited over 1400 individuals, both HIV-positive and negative of differing age groups with and appropriate control population in order to determine the effects HIV has on an number of outcomes including ageing, medical conditions and healthcare utilisation. Approximately 30% of the POPPY cohort are women and specific aspects of women’s health will be assessed.
Preliminary analysis of first 540 subjects who entered POPPY presented at BHIVA 2015
Background and justification for the study

Women’s experiences of ageing with HIV: personal, clinical and social care responses to the challenge of ageing with HIV in the UK

Chief Investigator: Jacqui Stevenson
This research will explore the experiences and needs of women growing older with HIV in London. It aims to add to the body of evidence around ageing and HIV, as people live longer with HIV due to effective treatment, and older people acquire and are diagnosed with HIV. With a specific focus on women and the gendered experiences of ageing, this research explores how women are responding and adapting to ageing with HIV, with a focus on community, social support, social and healthcare needs and the role of the State and third sector services in meeting these needs.
The research will be conducted by Jacqui Stevenson, a PhD student at the University of Greenwich in the department of Family Care and Mental Health. The research is being carried out within this department under supervision, and has been reviewed and approved by the University Research Ethics Committee.
The research adopts a participatory, gendered and assets-based approach, and qualitative methods. The research will be conducted in different stages, running roughly in sequence but with some overlap:

  1. Documentary analysis of existing literature, including a systematic review of social intervention research.
  2. Participatory workshops and consultation to develop research questions and themes, and involve people, especially women living with HIV, in constructing the research design and interpreting emerging findings.
  3. Policy review and key stakeholder interviews, with clinicians, service providers and other relevant experts.
  4. Life story interviews, with women living with HIV aged 50 and over.

If you are interested in finding out more about the research, have materials that you think should be included in the literature review or would be interested in participating in a workshop, stakeholder interview or life story interview please contact Jacqui at j.k.stevenson@gre.ac.uk.